The Lab of Ageing and Molecular Medicine
ABOUT OUR LAB
At this Lab, we are dedicated to advancing the understanding of ageing and molecular medicine. Our team of experts utilizes multi-omics approaches to delve into the complexities of ageing processes, aiming to uncover insights that can contribute to the development of molecular and precision medicine. We are committed to pushing the boundaries of scientific research and employing innovative methods to unravel the intricacies of ageing.
Research Topics
Our lab focuses on two main research areas: telomere replication and small RNAs, leveraging molecular biology, cell biology, and multi-omics approaches. Our goal is to advance understanding in these fields and contribute to the development of treatments for aging and aging-related diseases.
Telomore Replisome Identification
Our previous study developed QTIP-iPOND, a de novo method to isolate the telomere replisome, identifying 139 novel proteins potentially involved in telomere replication. Notably, many showed nucleolar localisation, suggesting a functional link between the nucleolus and telomeres in coordinating resources for efficient replication.
Mechanism on Small-Activating RNA
We aim to elucidate the mechanism of action of small-activating RNA (saRNA)—a specific type of small RNA that can increase gene expression—and its role in drug discovery, with a focus on developing new treatments for autoimmune diseases
News & Events
Nov 2025
Congrats Lily and Li-Mei on your direct admission to the Master’s program in the Department of Life Sciences, NCHU!
They will stay in the Lin Lab to investigate the functions of nucleolar proteins at telomeres and their roles in ageing!
25 Aug 2025
Gabi will be presenting at the 2025 Biochemistry and Molecular Biology Autumn Camp
Come join me at the meeting, October 24–26!
Our Team
Courses
Cell Biology
Tumour Cell Biology
Ageing and Ageing-associated Diseases
Omics Applications
By An-Tzu
Latest Publications
